The Shadow returned to network airwaves with the episode "The Death House Rescue" on September 26, 1937, over the Mutual Broadcasting System. Thus began the "official" radio drama, with 22-year-old Orson Welles starring as Lamont Cranston, a "wealthy young man about town." Once The Shadow joined Mutual as a half-hour series on Sunday evenings, the program was broadcast by Mutual until December 26, 1954. Welles did not speak the signature line, "Who knows what evil lurks in the hearts of men?" Instead, Readick did, using a water glass next to his mouth for the echo effect. The famous catchphrase was accompanied by the strains of an excerpt from Opus 31 of the Camille Saint-Saëns classical composition, Le Rouet d'Omphale.WIKIPEDIA
Three minutes into the music.